The synthesis of 10-(4-methylpiperazino)dibenzo (b,f)thiepin and related compounds. Neurotropic and psychotropic agents.
CHEMICAL & PHARMACEUTICAL BULLETIN(1976)
摘要
The preparation of 10-(4-methylpiperazino) dibenzo [b, f] thiepin (16a) and related Compounds is described. The reduction of 16a in an acidic medium yield the dihydro derivative (21) which was pharmacologically a valuable compound. Many of the compounds in this series showed marked neuroleptic effects similary to octoclotepine (2).
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关键词
related compounds,psychotropic agents,synthesis
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