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Synthesis and antimycobacterial activity of nitroxanthones. 2nd communication: antimycobacterial activity.

W G Ibrom,K J Schaper, A W Frahm

Arzneimittel-Forschung（1997）

Cited 26|Views1
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Abstract
The mono-, di-, tri- and tetranitroxanthones have been tested against different mycobacteria by means of the Agar diffusion method resulting in minimum inhibitory concentrations (MIC) and for more precise interpretation by means of the bacterial growth kinetics method. Nitroxanthones with the 2,4-dinitro-substitution pattern show activities beyond 1 microgram/ml.
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Key words
antimycobacterial activity,nitroxanthones
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