Anterior uveitis associated with high-dose cytosine arabinoside.

Purpose: To report a case of anterior uveitis associated with high-dose cytosine arabinoside (Ara-C) treatment. Design: Observational case report. Methods: A 14-year-old girl was seen for pain, redness, and photophobia shortly after finishing a cycle of high-dose Ara-C. Results: Portable slit-lamp examination revealed bilateral diffuse fine keratic precipitates, indicative of a nongranulomatous anterior uveitis. This was treated successfully with a course of topical prednisolone acetate 1%. Conclusions: Ophthalmologists who are asked to evaluate patients on high-dose Ara-C for a "red eye" should consider anterior uveitis as a potential diagnosis.