Association between beta-adrenoceptor gene polymorphisms and relative response to beta 2-agonists and anticholinergic drugs in Japanese asthmatic patients.

Koichiro Asano,Wakako Yamada-Yamasawa,Hiroyasu Kudoh,Tatsu Matsuzaki,Takahiro Nakajima,Haruhiko Hakuno,Rika Hiraoka,Koichi Fukunaga,Tsuyoshi Oguma,Koichi Sayama,Kazuhiro Yamaguchi,Akira Nagabukuro,Yosuke Harada,Akitoshi Ishizaka

Respirology (Carlton, Vic.)（2010）

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摘要

The ADRB2 A46G polymorphism was associated with a relatively greater bronchodilator responsiveness to beta(2)-agonists even in elderly asthmatic patients and smokers.

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关键词

airway reversibility,anticholinergic agent,asthma,oxitropium bromide,procaterol hydrochloride

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