Synthesis of reduced xanthatin derivatives and in vitro evaluation of their antifungal activity.
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY（2008）
Abstract
The synthesis of new xanthanolide derivatives is reported starting from xanthatin, a sesquiterpenic lactone isolated from Xanthium macrocarpum ( Asteraceae). In vitro evaluation of their antifungal activity has been investigated.
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Key words
antifungal agents,sesquiterpenic lactone,xanthanolide,Candida glabrata,Candida albicans,Aspergillus fumigatus
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