Hepatocellular carcinoma: the search for innovative adjuvant therapies.
Oncology (Williston Park, N.Y.)(2009)
Abstract
This review summarizes the current data on efficacy and rationale of adjuvant treatment for hepatocellular carcinoma (HCC) after orthotopic liver transplantation (OLT). The authors review prognostic factors for disease recurrence and adjuvant therapy after OLT, including systemic chemotherapy, intra-arterial chemoembolization, immunosuppressant effects, and sorafenib (Nexavar). Several interesting questions are raised in the article, including: (1) When is the best time to apply systemic chemotherapy?
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Key words
hepatocellular carcinoma,innovative adjuvant therapies
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