Optical tomographic imaging of tumor response to anti-angiogenic drugs in small animals
New York, NY（2010）
摘要
Using diffuse optical tomography we have imaged early vascular responses to anti-angiogenic treatments in a small animal tumor model. Images acquired from 1 to 7 days after drug administration show measurable changes in hemoglobin concentration. There are observable differences between mice treated with anti-angiogenic drugs and mice that receive a placebo treatment.
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关键词
biochemistry,blood vessels,drugs,molecular biophysics,optical tomography,proteins,tumours,anti-angiogenic drugs,anti-angiogenic treatments,diffuse optical tomography,early vascular responses,hemoglobin concentration,mice,placebo treatment,small animals,tumor model,tomography,optical imaging,optical scattering,cancer
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