Quantifying the short-term effects of deep brain stimulation surgery on bradykinesia in Parkinson's disease patients
Biomedical Engineering（2014）
Abstract
Clinical scale-based follow-up of patients undergoing bilateral subthalamic deep brain stimulation (STN-DBS) surgery has shown inconsistent effects on bradykinesia in Parkinson's disease patients. Furthermore, quantitative assessment of STN-DBS effect on bradykinesia has not been fully explored yet. Our group uses multisensory kinematic technologies to study short-term and long-term DBS effects on Parkinson's disease. In this paper we present a kinematic analysis of the short term (3 month) effects of STN-DBS on bradykinesia in five PD patients and compare the results with data obtained from healthy age-matched controls.
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Key words
biomechanics,brain,diseases,kinematics,neuromuscular stimulation,surgery,parkinson's disease,stn-dbs short term effects,stn-dbs surgery effect quantitative assessment,bilateral subthalamic deep brain stimulation,bradykinesia,healthy age-matched controls,long-term dbs effect,multisensory kinematic technologies,time 3 month,deep brain stimulation,objective measures,slowness of movement,hafnium,biomedical engineering,decision support systems
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