Numerical and experimental analysis of factors leading to suture dehiscence after Billroth II gastric resection

•The main goal of this study was to numerically quantify risk of duodenal stump blowout after Billroth II (BII) gastric resection.•Our hypothesis was that the geometry of the reconstructed tract after BII resection is one of the key factors that can cause increased duodenal pressure and consequently duodenal dehiscence.•If surgeon decide to perform BII type of reconstruction, findings obtained by this preoperative simulation are very useful in terms of minimizing the risk of duodenal dehiscence.