Uncovering influence links in molecular knowledge networks to streamline personalized medicine
Journal of Biomedical Informatics（2014）
Abstract
•RIIG infers influence relations among biomarker proteins and biological pathways.•RIIG uncovers patient-specific complex relationships among biological entities.•RIIG facilitates finding effective drug targets in a personalized medicine setting.•RIIG bridges curated biomedical knowledge and causal reasoning with clinical data.
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Key words
RDF inference,Morphoproteomics,Systems pathology,Theranostics,Personalized medicine
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