Simian hemorrhagic fever virus: Recent advances.

•SHFV induces hemorrhagic fever in macaques but not in African nonhuman primates.•SHFV infection of macaque but not baboon cells induces proinflammatory cytokines.•Unique N- and C-terminal genes encoded by SHFV were functionally analyzed.•PLP1γ can cleave at upstream sites as well as at the expected downstream site.•Eight minor structural proteins are required for infectious virus production.