FOXD1 promotes breast cancer proliferation and chemotherapeutic drug resistance by targeting p27.
Biochemical and Biophysical Research Communications(2015)
摘要
•FOXD1 is up-regulated in breast cancer tissues.•FOXD1 promotes breast cancer cell proliferation and chemoresistance by inducing G1 to S transition.•FOXD1 transcriptionally suppresses p27 expression.
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关键词
FOXD1,p27,Cell cycle,Drug resistance,Breast cancer
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