Self-assemblied nanocomplexes based on biomimetic amphiphilic chitosan derivatives for protein delivery.

Minming Wu,Hongwei Dong,Kai Guo,Rong Zeng,Mei Tu,Jianhao Zhao

Carbohydrate Polymers（2015）

Cited 15|Views5

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Abstract

•Novel amphiphilic biomimetic chitosan derivative DCA–PCCs was synthesized.•BSA and DCA–PCCs can self-assemble to form spherical nanocomplexes.•BSA/DCA–PCCs nanocomplexes show excellent cytocompatibility and hemocompatibility.•BSA/DCA–PCCs nanocomplexes exhibited a sustained drug release behavior.

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Key words

Biomimetic,Chitosan,Self-assembly,Nanocomplexes,Protein delivery

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