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Synthesis and anticancer properties of fucoidan-mimetic glycopolymer coated gold nanoparticles.

Tengdelius Mattias,Gurav Deepanjali,Konradsson Peter,Påhlsson Peter,Griffith May,Oommen Oommen P

CHEMICAL COMMUNICATIONS（2015）

Cited 42|Views10
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Abstract
Gold nanoparticles coated with fucoidan-mimetic glycopolymers were synthesized that displayed good colloidal stability and promising anti-cancer properties. Fucoidan mimetic glycopolymers on their own were nontoxic, while glycopolymer coated gold nanoparticles displayed selective cytotoxicity to human colon cancer cell lines (HCT116) while it was non-toxic to mouse fibroblast cells (NIH3T3).
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Key words
chemical sciences,clinical medicine
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