Assessment of long-term health risks after accidental exposure using haemoglobin adducts of epichlorohydrin.

•A human biomonitoring study was performed to evaluate internal exposure after accidental release of epichlorohydrin.•Haemoglobin adducts of epichlorohydrin, the N-(3-chloro-2-hydroxypropyl)valine (CHPV) and the N-(2,3-dihydroxypropyl)valine (DHPV), were measured in blood.•In 6 out of 628 samples, CHPV adduct levels above the LOQ of 25pmol/g ranged from 32.0 to 116.4pmol/g globin.•DHPV was not detected above the LOD of 10pmol/g globin in any of the blood samples.•Based on the quantified CHPV adduct values, estimates of the cumulative additional lifetime cancer risks range from 2.61×10−8 to 9.48×10−8.