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Effects of detyrosinated tubulin on Na+,K+-ATPase activity and erythrocyte function in hypertensive subjects.

Marina R Amaiden,Verónica S Santander,Noelia E Monesterolo,Ayelen D Nigra,Juan F Rivelli,Alexis N Campetelli,Juan Pie,Cesar H Casale

FEBS Letters（2015）

Cited 17|Views50
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Abstract
•Detyrosinated tubulin is able to inhibit the NKA activity.•Erythrocytes of hypertensive subjects have a reduced content and activity of TTL.•GluTub levels and NKA activity are related to erythrocyte deformability.•The mechanism explains involvement of tubulin in hypertension.
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GluTub,AcTub,TyrTub,NKA,TTCP,TTL,PAGE,PMSF
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