Two new dimeric naphthoquinones with neuraminidase inhibitory activity from Lithospermum erythrorhizon
Natural Product Research(2015)
摘要
The crude methanol extract of roots of Lithospermum erythrorhizon was subjected to successive chromatographic fractionation which afforded two new dimeric naphthoquinone derivatives shikometabolin E (2) and shikometabolin F (3) as well as one known compound shikometabolin A (1). The structures of compounds 1–3 were elucidated by using UV, MS, 1D and 2D NMR spectroscopic analysis. The two new dimeric naphthoquinone derivatives showed significant neuraminidase inhibitory activities.
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关键词
Lithospermum erythrorhizon,dimeric naphthoquinone,neuraminidase inhibitory
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