Identification of anti-moesin antibodies in the serums of patients with antiphospholipid syndrome.

Xiaoyi Lin,Qian Liang,Lin Lin,Qiulan Ding,Xuefeng Wang,Ying Wang

Thrombosis Research（2015）

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摘要

•We identified anti-moesin-N antibodies in 73 % of serum samples from 100 patients with APS.•The elevated anti-moesin-N Abs levels significantly correlated with plasma levels of anti-β2GPI.•Murine anti-moesin-N mAb could promote platelet activation and aggregation in vitro.

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关键词

APS,aPL,aCL,anti-β2GPI,LA,ERM,anti-moesin Abs,anti-moesin mAbs,anti-moesin-N Abs,anti-moesin-C Abs,RA,AA,ANCA,s,min,h,RT-PCR,ELISA,TBS,BSA,TMB,A,SD,CO,PBS,PC5,FITC,Mnx,MFI,RGDS,PAC-1,GP,PRP,PPP,PAR,PAIR

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