The constellation of dietary factors in adolescent acne: a semantic connectivity map approach.

Background Different lifestyle and dietetic factors have been linked with the onset and severity of acne. Objective To assess the complex interconnection between dietetic variables and acne. Methods This was a reanalysis of data from a case-control study by using a semantic connectivity map approach. 563 subjects, aged 10-24 years, involved in a case-control study of acne between March 2009 and February 2010, were considered in this study. The analysis evaluated the link between a moderate to severe acne and anthropometric variables, family history and dietetic factors. Analyses were conducted by relying on an artificial adaptive system, the Auto Semantic Connectivity Map (AutoCM). Results The AutoCM map showed that moderate-severe acne was closely associated with family history of acne in first degree relatives, obesity (BMI >= 30), and high consumption of milk, in particular skim milk, cheese/yogurt, sweets/cakes, chocolate, and a low consumption of fish, and limited intake of fruits/vegetables. Conclusion Our analyses confirm the link between several dietetic items and acne. When providing care, dermatologists should also be aware of the complex interconnection between dietetic factors and acne.