Developmental pathways activated in melanocytes and melanoma.

Jianglan Liu,Mizuho Fukunaga-Kalabis,Ling Li,Meenhard Herlyn

Archives of Biochemistry and Biophysics（2014）

引用 77|浏览5

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摘要

•Melanocyte development and melanoma progression share similarities.•Developmental genes critical for melanocyte and melanoma development are described.•Several genetic pathways are highlighted including Notch, Wnt, Endothelins and Sox.

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关键词

Melanocytes,Melanoma,Signaling pathways,Notch,Wnt,Beta-catenin,Endothelin,Sox9,Sox10,MITF

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