皮肤原发性外周原始神经外胚叶肿瘤

Xiao-gang XIONG,Ye-qiang LIU,Wen-bin CHEN,Xiao XU,Qing LEI,Ying ZHANG,Shi-hong HU,Ping ZHANG,Qiu-he SONG,Wu-hua TONG,Ying WANG,Jun LU,Ze-ying YU,Fang-yuan CHEN

Journal of Clinical Dermatology（2011）

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Abstract

报告1例发生于皮肤的原发性外周原始神经外胚叶肿瘤.患者女,65岁.躯干、大腿内侧多发性丘疹、结节3个月.皮损组织病理检查:表皮大致正常,表皮与瘤团间有境界带,肿瘤深达皮下,片状生长,由深染的小至中等大的圆细胞组成,瘤细胞胞核深染,核仁明显,胞质淡染,细胞排列拥挤,个别细胞有异常核分裂象.免疫组化检查:CD99、波形蛋白(vimentin)、神经特异性烯醇化酶(NSE)均阳性.电子显微镜检查:瘤细胞内有神经内分泌颗粒.根据患者临床表现和组织病理、免疫组化及电镜检查结果,诊断为皮肤原发性外周原始神经外胚叶肿瘤.

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Key words

Cutaneous,Peripheral primitive neuroectodermal tumor,Primary

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