Synthesis and anticoagulant action of sulfated chitosan/Eu2O3 nano-oxides hybrid materials

The Eu2O3 nano-oxides surface was modified by 3-glycidoxypropyltrimethoxysilane. The hybrid materials of sulfated chitosan and Eu2O3 nano-oxides were prepared by the method of graft. And the materials were characterized by IR, TG and SEM. The results showed that the sulfated chitosan was grafted on the surface of Eu2O3 nano-oxides, which was modified by KH-560. The results of cell adhesion experiment showed that the material had lower cell toxicity and better cell adhesion. The experiment of anticoagulant showed that the material has better anticoagulant action.