Nitrobenzene Induces DNA Damage in Tobacco

Guo Changhong,Cao Yuwei,Li Rui,Si Liang, Ma Jun,Yuan Zening

Bioinformatics and Biomedical Engineering（2010）

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摘要

Single-cell gel electrophoresis (SCGE) is a useful technical tool to detect DNA damages. In this work, tobacco plants (Nicotiana tabacum var. xanthi) were cultivated in different concentrations of nitrobenzene, and the DNA damages were analyzed by using SCGE. The results showed that the DNA damages increased with increasing nitrobenzene concentrations. Results of the present study suggest that nitrobenzene is one of genotoxic pollutan and may be a genotoxdic risk to human health.

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关键词

environmental pollution,single-cell gel electrophoresis (scge),nicotiana tabacum var. xanthi,single cell gel electrophoresis,dna damage detection,botany,genotoxic pollutant,air pollution,organic compounds,dna damage,tobacco plants,biological techniques,molecular biophysics,molecular configurations,electrophoresis,nitrobenzene,nitrobenzene induced dna damage,dna,scge,maintenance engineering,reactive power,organisms,electrokinetics

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