UPLC-MS/MS测定降糖类中药制剂及保健品中8种化学药的研究
Chinese Pharmaceutical Journal(2009)
Abstract
目的 建立一种测定降糖类中药制剂及保健品中违禁添加8种化学药的超高效液相-串联四级杆质谱方法.方法 使用超高效液相-串联四极杆质谱的多反应监测(MRM)模式测定.结果 8种化学药测定的线性范围在0.5~200.0 μg·L-1之间,r分别在0.997 1~0.999 8之间;盐酸二甲双胍、盐酸苯乙双胍、格列奇特、盐酸吡格列酮、格列吡嗪、格列美脲、格列苯脲和格列喹酮的检出限分别为5.2,1.1,5.4,0.2,5.1,0.2,0.7和3.1 μg·kg-1;3个水平的回收率分别在84.3%~121.1%间.结论 该方法快速、准确、灵敏,可用于降糖类中药制剂及保健品中违禁添加8种化学药的测定.
MoreTranslated text
Key words
Anti-iabetic,Health foods,Traditional chinese medicines,Triple-quadrupole tandem mass spectrometer,UPLC
AI Read Science
Must-Reading Tree
Example
![](https://originalfileserver.aminer.cn/sys/aminer/pubs/mrt_preview.jpeg)
Generate MRT to find the research sequence of this paper
Chat Paper
Summary is being generated by the instructions you defined