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狼疮性肾炎患者肾组织Epstein-Barr病毒感染状况及其致病作用初探

Xiao-xia YU,Hua-feng LIU,Jing-li TAO,Chen YANG,Shang-mei LI,Xiao-wen CHEN,Dong LIANG,De-shen TANG

Chinese journal of microbiology and immunology（2009）

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Abstract
并感染之间以及不同病理类型之间差异均无统计学意义(P＞0.05).肾组织EBER和EBV LMP1表达阳性的LN患者的血清中anti-Sm-Ab阳性率显著高于两标记物表达阴性的LN患者(EBER:34.3%vs 8.7%,EBV LMP1:35.3%vs 9.1%,P均＜0.05).结论 肾组织EBV感染可能参与了LN的发病,其机制可能部分与诱导机体产生自身抗体anti-Sm-Ab有关.
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Key words
Autoantibody,Epstein-Barr virus,Lupus nephritis
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