急性髓细胞白血病患者外周血及骨髓CD87表达的改变

目的 探讨急性髓细胞白血病(AML)患者外周血及骨髓CD87表达的改变.方法 应用流式细胞术(FCM)检测了30例AML患者(M12例,M26例,M48例,M514例)外周血及骨髓CD87表达,应用配对t检验分析外周血及骨髓CD87表达的改变.结果 14例M5患者骨髓CD87表达为9.47%～80.32%,外周血CD87表达为11.49%～87.46%;8例M4患者骨髓CD87表达为14.27%～46.28%,外周血CD87表达为14.79%～47.19%;6例M2患者骨髓CD87表达为4.67%～34.26%,外周血CD87表达为8.96%～39.78%;2例M1患者骨髓CD87表达为3.56%～7.69%,外周血CD87表达为5.21%～8.96%.30例急性髓细胞性白血病外周血及骨髓CD87表达差异有统计学意义(f=3.13,P＜0.05).结论 AML患者外周血及骨髓CD87表达有变化,外周血CD87表达高于骨髓,推荐应用外周血代替骨髓检测CD87表达.