Effect of glutamine dipeptides on the postoperative nutrition and immunofuncfion of patients with esophagus carcinom

Objective: To evaluate the effect of glutamine dipeptides-enhanced parenteral nutrition on the postoperative nutrition and immunofunction of patients with esophagus carcinoma. Methods: One hundred patients with esophagus carcinoma were randomly divided into Gln group and control group. All patients were administered with parenteral nutrition for seven days, and patients in Gln group were simultaneously added with alanyl glutamine solution (0.4 g/kg per day). The serum album (ALB) level, T lymphocyte subgroups, IgA, IgG, IgM, and body mass index (BMI) were measured. Results: The ALB level, IgA, IgG, and BMI were (42.8 ± 3.4) g/L, (2.7 ± 2.2) g/L, (10.8 ± 2.2) g/L, and (19.1 ± 1.6) kg/m 2 in Gln group on the sixth postoperative day, which were significantly higher than those in control group (All P < 0.05). Conclusion: Alanyl glutamine solution-enhanced TPN therapy can improve the postoperative nutrition and immunofunction in patients with esophagus carcinomas.