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Interaction Between Sm(Iii)(Mtb)(2) Complex And Dna By Spectrometry

CHINESE JOURNAL OF INORGANIC CHEMISTRY(2006)

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摘要
The interaction between Sm(M)(MTB)(2) complex and Herring Sperm DNA has been studied by UV-Vis spectral, Fluorescence spectral in buffer solution of Tris-HCl (pH=7.25) using Neutral Red (NR) as a probe. The intercalation and electrostatic manner are confirmed to be the two major modes for interaction between Sm(III) (MTB)(2) complex and Herring Sperm DNA. The balance constant of Sm(M)(MTB)(2) rare earth metal complex and Herring Sperm DNA is K=4.10 x 10(4) L(.)mol(-1). The results indicate that biological functions of Herring Sperm DNA are changed to a certain extend due to the interaction between Sm(III)(MTB)(2) rare earth metal complex and Herring Sperm DNA.
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关键词
Sm(III)(MTB)(2) complex, methyl thymol blue eymplexon, neutral red, DNA
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