电离辐射对人大肠癌 HT29细胞乙酰肝素酶 mRNA表达影响的研究

AIM:To study the effect of exposure to 8 MV X- ray irradiation on heparanase mRNA expression in human colorectal carcinoma HT29 cells.METHOD:In situ hybridization technique was used to study the expression of heparanase mRNA in HT29 cells.RESULTS:After exposure to the dose of 2 Gy,the heparanase mRNA expression in HT29 cells was significantly weakened.CONCLUSION:Radiation may inhibit the metastasis ability of HT29 cells.