化学发光免疫法与免疫放射法检测血清TSH的临床价值比较
Hunan yi ke da xue xue bao = Hunan yike daxue xuebao = Bulletin of Hunan Medical University（2003）
Abstract
目的: 比较化学发光免疫分析(CLIA)及免疫放射分析(IRMA)检测血清促甲状腺激素(TSH)对诊断甲状腺机能亢进(甲亢)及甲状腺机能减低(甲减)的临床价值.方法: 用CLIA与IRMA对112例正常人、120例甲亢病人、58例甲减病人血清标本TSH含量进行测定.结果: 两法的相关性良好(r＝0.98,P＜0.01),但CLIA对甲亢及甲减的诊断临床符合率比IRMA高,且CLIA的精密度(批内变异)和重复性(批间变异)均优于IRMA. 结论: CLIA对甲亢及甲减的诊断优于IRMA.
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Key words
thyroid-stimulating hormone,hypothyroidism,immunoradiometric assay,chemiluminescent immunoassay,hyperthyroidism
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