Primary study on the relationship between calcium acetate and kidney stone

Chinese Pharmacological Bulletin(2000)

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Abstract
Aim To investigate the relationship between calcium acetate as supplement and kidney stone by giving calcium acetate to the experimental rats both with normal physiological condition and with abnormal oxalate metabolism. METHODS: Observations of the stone formation were made after 8 week feeding of Wistar rats with calcium acetate and classical calcium supplement-calcium carbonate. RESULTS: In the experimental condition, calcium acetate did not induce kidney stone in rats with normal physiological condition, however, an increased risk was observed in the animals with abnormal oxalate metabolism. CONCLUSION: Calcium acetate is a safe calcium supplement when it is used property; oxalate-rich food should be avoided at the time of calcium supplementation.
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Key words
Calcium acetate,Calcium supplement,Kidney stone
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