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Study on radioiodine labelled tissue plasminogen activator (tPA)

Weiyi Li,Guoxian Cao,Rongjun Zhang

He Jishu/Nuclear Techniques（1994）

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Abstract
In this paper the study on 125I labelled tPA and its in vivo distribution in animal tumor was reported. The tumor/tissue ratio of 125I-tPA in mouse in different time phase was obtained. Experimental results suggest that tPA can accumulate in tumor and may be a potential tumor imaging agent, especially for brain, stomach and intestine.
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