Genetic variability of HPV-58 E6 and E7 genes in Southwest China

Lijuan Yang,Hongying Yang,Junying Chen,Xinwei Huang,Yue Pan,Duo Li,Xiaojie Ding,Kun Wu,Xinan Shi, Juanjuan Fu,Haijing Shi,Shaohui Ma,Qiangming Sun

Infection, Genetics and Evolution（2014）

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摘要

•We investigated the prevalence and E6/E7 variants of HPV-58 in Southwest China.•4 single nucleotide changes were observed in HPV-58 E6 sequences.•8 single nucleotide changes were observed in HPV-58 E7 sequences.•HPV-58 E6/E7 variants identified belonged to the Southeast Asia lineage.•There was no evidence of positive selection in sequence alignment of HPV-58 E6/E7.

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关键词

HPV-58,E6 gene,E7 gene,Variation,Cervical cancer

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