Synthesis And Anticoccidial Activities Of Novel N-(2-Aminophenyl)-2-Quinazolinone-Acetamide Hydrochloride

Eight novel N-(2-aminophenyl)-2-quinazolinone-acetamide hydrochloride were synthesized and their structures were identified by 1 H NMR, MS and IR spectra. Seven of the new compounds were chosen for anticoccidial activity test and the results showed that N-(2-aminophenyl)-2-(6-methyl-8-bromo quinazolinone) acetamide hydrochloride (3h) exhibited anticoccidial activity against Eimeria tenella in the chicken' diet with a dose of 18 mg/Kg.