One-pot tandem cyclization of enantiopure asymmetric cis-2,5-disubstituted pyrrolidines: Facile access to chiral 10-heteroazatriquinanes.
BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY（2013）
Abstract
A series of chiral 10-heteroazatriquinanes were synthesized from enantiopure asymmetric cis-2,5-disubstituted pyrrolidines through a one-pot tandem cyclization procedure. The structures and configurations of these new chiral 10-heteroazatriquinanes are confirmed by X-ray single-crystal diffraction analysis.
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Key words
cis-2,5-disubstituted pyrrolidine,10-heteroazatriquinane,tandem cyclization,X-ray single-crystal diffraction analysis
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