A Facile, Regioselective And Controllable Bromination Of Aromatic Amines Using A Cubr2/Oxone (R) System
RSC ADVANCES(2013)
摘要
A combination of cupric bromide and Oxone (R) serves as a facile, mild and effective reagent for the bromination of aromatic amines. Primary, secondary and tertiary aromatic amines are all suitable substrates. The reaction possesses high regioselectivity and functional group tolerance, and mono- and multi-brominated products can be obtained controllably in moderate to excellent yields.
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