Analysis of micronomicin by liquid chromatography with pulsed electrochemical detection.

Yaozuo Yuan,Shruti Chopra,XiaoLan Deng,Mei Zhang,XiaLei Fan,Changqin Hu,Shaohong Jin,Ann Van Schepdael,Erwin Adams

Journal of Chromatography A（2013）

引用 10|浏览36

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摘要

•An LC–PED method was established for the analysis of MCR and its related substance.•A quadruple-potential waveform was selected as detection waveform.•Two main unknown impurities were characterized by LC–MS.•9 of 18 impurities detected in the chromatogram were located.

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关键词

LC–PED,Quadruple potential waveform,Micronomicin sulfate,Aminoglycoside antibiotics

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