Surface functionalization of styrenic block copolymer elastomeric biomaterials with hyaluronic acid via a "grafting to" strategy

Xiaomeng Li,Shifang Luan,Shuaishuai Yuan,Lingjie Song,Jie Zhao,Jiao Ma,Hengchong Shi,Huawei Yang,Jing Jin,Jinghua Yin

Colloids and Surfaces B: Biointerfaces（2013）

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Abstract

•Biocompatibility was imparted to SBC with HA via a “grafting to” strategy.•The HA-modified samples presented a low adhesiveness to fibroblast.•The HA modification stimulated the growth of fibroblast on the substrates.•Fibroblast growth exhibited a strong dependence on HA molecular weight.

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Key words

Styrenic block copolymer (SBC),Hyaluronic acid (HA),Surface functionalization,Hemocompatibility,Cytocompatibility

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