Determination of Pseudoginsengenin DQ in rat plasma by UPLC-MS/MS and application of the method in a pharmacokinetic study.

Hongmei Gao, Zhuo Li,Pingya Li,Meiyu Lin,Liu Han,Fang Wang,Jinping Liu

Journal of Chromatography B（2013）

引用 8|浏览4

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摘要

•A UPLC–MS/MS method was developed for determination of pseudoginsengenin DQ.•Detection was performed by ESI+ in multiple reaction monitoring (MRM) mode.•The validation was all satisfactory in all the biological matrices examined.•The method was applied to pharmacokinetic study with administration of 15mg/kg PDQ.

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关键词

Pseudoginsengenin DQ,UPLC–MS/MS,Pharmacokinetics

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