Steroidal glycosides from Reineckia carnea herba and their antitussive activity.
PLANTA MEDICA(2013)
摘要
Two new steroidal glycosides, 1 alpha,3 alpha-dihydroxy-5 beta-pregn-16-en-20-one 3-O-alpha-L-rhamnopyranoside (1) and 1 beta,3 beta,27-trihydroxycholest-16-en-22-one 1,3-di-O-alpha-L-rhamnoside (2), along with seven known steroidal glycosides (3-9), were isolated from Reineckia carnea herba. Their structures were determined by detailed analysis of their 1D- and 2D-NMR and MS spectra. Compound 9 was isolated for the first time from the Reineckia genus. Except for 8, compounds 2, 3, 4, 5, 6, 7, and 9 displayed clear in vitro antitussive activity.
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关键词
Reineckia carnea,Liliaceae,steroidal glycosides,antitussive
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