The sensory disturbances in patients stroke combined with small fiber neuropathy

Objective: To study the combined sensory impairment in stroke patients in skin around the nerve fiber damage. Methods: 20 cases stroke patients and 20 healthy controls of age and sex matched were collected. Skin biopsy was performed and skin taken to observe the morphology of small nerve fibers. Epidermal nerve fiber density declined in stroke group and negatively correlated with age, duration. Comparison between two groups yielded non discriminatory nerve fiber density difference as well as no difference in gender, age within each group was seen. Conclusion: stroke patients with combined sensory disorders have epidermal nerve fiber damage.