MiR-29a modulates the angiogenic properties of human endothelial cells.
Biochemical and Biophysical Research Communications（2013）
Abstract
•miR-29a may be stimulated by hypoxia in HUVEC.•miR-29a regulates cell cycle, proliferation and tube network formation of HUVEC.•HMG box-containing protein-1(HBP1) is a direct target of miR-29a.•miR-29a has a potential value for treating angiogenesis-associated diseases.
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Key words
miRNA,miR-29a,HUVEC,HBP1,DFO,CCK-8,UTR,FACS
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