Discovery of novel 2-piperidinol-3-(arylsulfonyl)quinoxalines as phosphoinositide 3-kinase α (PI3Kα) inhibitors.

Bioorganic & Medicinal Chemistry（2012）

引用 19|浏览6

暂无评分

摘要

A series of novel 2-piperidinol-3-(arylsulfonyl)quinoxalines, as exemplified by compound WR23, was synthesized and evaluated as PI3Kα inhibitors.

查看译文

关键词

2-Piperidinol-3-(arylsulfonyl)quinoxaline,PI3Kα,pAkt,Antitumor activity

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要