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姑息放疗联合榄香烯治疗晚期NSCLC的临床疗效观察

Journal of Practical Oncology(2012)

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Abstract
目的 探讨姑息放疗联合榄香烯治疗晚期非小细胞肺癌(non-small cell lung cancer,NSCLC)的疗效.方法 回顾性分析157例Ⅳ期NSCLC病例,采用姑息放疗联合榄香烯治疗56例,姑息放疗联合姑息化疗35例,吉非替尼靶向治疗39例,单纯姑息放疗27例,运用SPSS 11.0统计软件包分析Ⅳ期NSCLC生存情况.结果 姑息放疗联合榄香烯治疗组的患者生存期高于姑息放疗联合姑息化疗组、吉非替尼靶向治疗组、单纯姑息放疗组,有效率分别为96.4%、77.1%、74.4%、66.7%.中位生存期分别为14月、8月、8月、5月(P<0.05),1年生存率分别为71.4%,44.0%,41.8%,21.6% (P =0.000),2年生存率分别为30.4%、2.0%、5.6%、0.0%(P=0.000).结论 姑息放疗联合榄香烯治疗晚期非小细胞肺癌可缓解症状,提高生活质量,延长生存时间.
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Key words
Carcinoma, non-small-cell lung/drug therapy,Carcinoma, non-small-cell lung/radiotherapy,Combined modality therapy,Palliative care,Retrospective studies,Sesquiterpenes/therapeutic use,Survival rate
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