Transforming Growth Factor beta1 Gene Variation Leu10Pro Affects Secretion and Function in Hepatic Cells

Xing Gu,Xin Ji,Le-Hua Shi,Chang-Hong Yi,Yun-Peng Zhao,Ai-Hua Wang, Lun-Gen Lu,Wen-Bo Yu,Chun-Fang Gao

Digestive Diseases and Sciences（2012）

引用 8|浏览28

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摘要

Our previous work revealed transforming growth factor beta1 (TGFβ1) gene polymorphisms are associated with susceptibility to hepatocellular carcinoma and liver cirrhosis. However, no further study of functional substitution in hepatic cells has yet been reported.

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关键词

Hepatocellular carcinoma (HCC),Liver cirrhosis,Genetic polymorphism,Transforming growth factor beta1 (TGFβ1)

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