Two new compounds from an endophytic fungus Alternaria solani.
JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH(2012)
Abstract
Two new secondary metabolites, named 7-dehydroxyl-zinniol (1) and 20-hydroxyl-ergosta-4,6,8(14),22-tetraen-3-one (2), were isolated from the culture of Alternaria solani, an endophytic fungal strain residing in the roots of Aconitum transsectum. Their structures were elucidated on the basis of comprehensive spectroscopic analyses including IR, ESI-MS, HR-ESI-MS, 1D and 2D NMR. Biological activity tests indicated that compound 1 showed moderate anti-HBV activity.
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Key words
Alternaria solani,Aconitum transsectum,7-dehydroxyl-zinniol,20-hydroxyl-ergosta-4,6,8(14),22-tetraen-3-one,anti-HBV activity
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