[Expression and significance of neutrophil gelatinase-associated lipocalin in renal interstitial fibrosis in rats].

The expression of NGAL significantly increases in UUO modal of rats. And it is closely correlated with MMP-9, TNF-α and TGF-β1. ACEI may influence the biological effects of NGAL by suppressing inflammatory responses, down-regulating the expression of TGF-β1 and regulating the expression and the activity of MMP-9.