Immunogenicity of Novel Sulfadimethoxide Conjugates
African journal of biotechnology(2011)
摘要
Sulfadimethoxine (SDM) is an antibiotic commonly added to animal feeds. Anti-SDM antibodies are useful for the detection of residual SDM in foods, feeds and biological fluids by ELISA. In this study, we show that SDM is immunogenic in rabbits when it is conjugated with soy 11S globulin or with beta-amylase. Rabbit anti-SDM antibodies obtained by immunization with SDM-11S and SDM-beta-amylase displayed low cross-reactivity against other sulfonamides, including sulfamethazine (SM2), sulfasulfonamides (SN), sulfadiazine (SD), sulfamethoxypyrazine (SMP), sulfalene (SMZ), sulfaquinoxaline (SQX). Thus, soy 11S globulin and beta-amylase are suitable carriers for the induction of anti-SDM antibodies and have the advantage of being cheaper that BSA.
更多查看译文
关键词
Sulfadimethoxine (SDM),sulfasulfonamides (SN),sulfadiazine (SD),sulfamethazine (SM2),sulfamethoxypyrazine (SMP),sulfalene (SMZ),sulfaquinoxaline (SQX),rabbit anti-SDM antibodies,soy 11S globulin,SDM-beta-amylase
AI 理解论文
溯源树
样例
![](https://originalfileserver.aminer.cn/sys/aminer/pubs/mrt_preview.jpeg)
生成溯源树,研究论文发展脉络
Chat Paper
正在生成论文摘要