Graphene oxide modified DNA electrochemical biosensors

One approach had been developed for the covalent modification of graphene sheets: amidation and esterification of graphene oxide (GO). Graphene oxide was synthesized by oxidizing graphite in strong acid and lots of oxygen-containing groups, such as hydroxyl and carboxyl processed in the carbon layers, made GO strongly hydrophilic activity as well as certain of chemical activity. This work researched a novel DNA biosensor which fabricated by immobilizing GO on Au electrode modified with mercaptoethylamine(MEA), was investigated by cyclic voltammetry. The results showed that graphite oxide was an excellent material and had a promising prospect in biosensor construction.