肝硬化时肠源性内毒素血症形成机制的研究进展
Chinese Journal of Integrated Traditional and Western Medicine on Digestion（2013）
Abstract
<正>大量实验证实,多种肝病尤其是慢性肝病不同程度伴随肠源性内毒素血症(intestinal endotoxemia,IETM)[1],其中肝硬化患者IETM的发生率为79.0%～92.0%[2],肝功能损害越重,内毒素水平越高[3]。肝硬化时肠道菌群失调,肠黏膜屏障功能减低,肝脏清除内毒素能力下降,内毒素水平升高,IETM发生率增加,IETM形成后进一步加重肝
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